ABM

In the seventies, two researchers from Penn State visited the Sao Paulo, Brazil area and discovered the local natives to be extremely healthy with a very low rate of disease. The longevity rate was disproportionately high with people living well over 100.

Their secret?

It was a simple mushroom, they told the researchers, the ABM mushroom (Agaricus Blazei Murill).

Subsequent studies over the next 25 years have shown the ABM to stimulate the immune system and promote natural mechanisms to battle infectious disease and cancers. ABM stimulates lymphocyte T-cell and Helper T-cell production.

The polysaccharide contained in ABM stimulates production of interferon and interleukin that indirectly function to destroy and prevent the proliferation of cancer cells. Additionally, ABM turned out to be a very powerful antiviral agent preventing viruses from entering tissues.

Normally, the polysaccharides found in fungus only affect solid cancers, however the polysaccharide in ABM is effective against Ehrich's ascites carcinoma, sigmoid colonic cancer, ovarian cancer, breast cancer, lung cancer, and liver cancer as well as against solid cancers.

Cancer IV Therapy - Japan:

In Japan, ABM, in an injectable form, was found to eliminate all cancerous tumors in 90% of the experimental mice. Additionally, when the mice were fed ABM as a preventative and then injected with a very powerful cancer causing agent (Sarcoma 180), 99.4% of them showed no tumor growth.

Conventional medicine has no preventive this powerful. 

The studies in Japan showed ABM to be 80% more effective than the world's number one cancer drug, PSK.

It contains much higher levels of beta glucans than the other medicinal mushrooms (Maitake, Shiitake, and Reishi) and stimulates NK (Natural Killer) cell activity. 

It should be noted that the beta-glucans in these mushrooms work best when taken with vitamin C.

The studies in Japan were so successful that today Japan is now buying over 90% of the available ABM from Brazil.

* A special note: Japan's chief chemotherapy for cancer comes from a mushroom and is nontoxic. Japan employs chemotherapeutic drugs that are toxic only after trying the nontoxic therapies first. At the time of this writing, according to the World Health Organization's statistics, Japan stands first in overall longevity while the US stands at 24th.  

Source: http://www.mnwelldir.org/docs/cancer1/altthrpy.htm

Source: http://www.euro-med.us/news/mushroom-extract.cfm

ABM

ABM

Dietary Supplementation With Agaricus Blazei Murill Extract Prevents Diet-Induced Obesity and Insulin Resistance in Rats.

Abstract: Dietary supplement may potentially help to fight obesity and other metabolic disorders such as insulin-resistance and low-grade inflammation. The present study aimed to test whether supplementation with Agaricus blazei murill (ABM) extract could have an effect on diet-induced obesity in rats.

Method: Wistar rats were fed with control diet (CD) or high-fat diet (HF) and either with or without supplemented ABM for 20 weeks.

Results: HF diet-induced body weight gain and increased fat mass compared to CD. In addition HF-fed rats developed hyperleptinemia and insulinemia as well as insulin resistance and glucose intolerance. In HF-fed rats, visceral adipose tissue also expressed biomarkers of inflammation.

ABM supplementation in HF rats had a protective effect against body weight gain and all study related disorders. This was not due to decreased food intake which remained significantly higher in HF rats whether supplemented with ABM or not compared to control. There was also no change in gut microbiota composition in HF supplemented with ABM.

Interestingly, ABM supplementation induced an increase in both energy expenditure and locomotor activity which could partially explain its protective effect against diet-induced obesity. In addition a decrease in pancreatic lipase activity is also observed in jejunum of ABM-treated rats suggesting a decrease in lipid absorption.

Conclusion: Taken together these data highlight a role for ABM to prevent body weight gain and related disorders in peripheral targets independently of effect in food intake in central nervous system.

Obesity (Silver Spring). 2012 Jun 7. doi: 10.1038/oby.2012.139.
Vincent M, Philippe E, Everard A, Kassis N, Rouch C, Denom J, Takeda Y, Uchiyama S, Delzenne NM, Cani PD, Migrenne S, Magnan C.
University Paris-Diderot, Sorbonne Paris Cité, Centre National de la Recherche Scientifique, Paris, France.

Source: http://www.ncbi.nlm.nih.gov/pubmed/22767281

ABM

An Extract of Agaricus blazei Murill Administered Orally Promotes Immune Responses in Murine Leukemia

Abstract: The edible mushroom (fungus) Agaricus blazei Murill (ABM) is a health food in many countries. Importantly, it has been shown to have antitumor and immune effects. There is no available information on ABM-affected immune responses in leukemia mice in vivo. Experimental Design. In this study, the authors investigated the immunopotentiating activities of boiled water-soluble extracts from desiccated ABM in WEHI-3 leukemia mice. The major characteristic of WEHI-3 leukemia mice are enlarged spleens and livers after intraperitoneal injection with murine leukemia WEHI-3 cells. Isolated T cells from spleens of ABM-treated mice resulted in increased T-cell proliferation compared with the untreated control with concanavalin A stimulation.

Results: ABM decreased the spleen and liver weights when compared with WEHI-3 leukemia mice and this effect was a dose-dependent response. ABM promoted natural killer cell activity and phagocytosis by macrophage/monocytes in leukemia mice in a dose-dependent manner. ABM also enhanced cytokines such as interleukin (IL)-1β, IL-6, and interferon-γ levels but reduced the level of IL-4 in WEHI-3 leukemia mice. Moreover, ABM increased the levels of CD3 and CD19 but decreased the levels of Mac-3 and CD11b in leukemia mice.

Conclusion: The ABM extract is likely to stimulate immunocytes and regulate immune response in leukemia mice in vivo.

Integr Cancer Ther. 2012 Mar;11(1):29-36.
Lin JG, Fan MJ, Tang NY, Yang JS, Hsia TC, Lin JJ, Lai KC, Sai-Chuen Wu R, Ma CY, Wood WG, Chung JG.
1China Medical University, Taichung, Taiwan.

Source: http://www.ncbi.nlm.nih.gov/pubmed/22637937